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Index > Protein center > Nr5a2(Gene name) > Mouse
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  • Nr5a2 (Gene name),
  • Nuclear receptor subfamily 5 group A member 2 (Protein name ),  NR5A2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Nr5a2(Lrh1);
    Protein name:
    Nuclear receptor subfamily 5 group A member 2;
    Alternative:
    Liver receptor homolog 1(LRH-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds DNA as a monomer (By similarity). Interacts with GRIP1, NCOA2 and NR0B2.
    Function:
    Binds to promoters containing the sequence element 5'-AACGACCGACCTTGAG-3'. Plays a role in the regulation of gene expression in liver and pancreas. May play a role in embryonic development.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    560
    Sequence:
    50:
    MSASLDTGDF | QEFLKHGLTA | IASAPGSETR | HSPKREEQLR | EKRAGLPDRH | 
    100:
    RRPIPARSRL | VMLPKVETEA | PGLVRSHGEQ | GQMPENMQVS | QFKMVNYSYD | 
    150:
    EDLEELCPVC | GDKVSGYHYG | LLTCESCKGF | FKRTVQNQKR | YTCIENQNCQ | 
    200:
    IDKTQRKRCP | YCRFKKCIDV | GMKLEAVRAD | RMRGGRNKFG | PMYKRDRALK | 
    250:
    QQKKALIRAN | GLKLEAMSQV | IQAMPSDLTS | AIQNIHSASK | GLPLSHVALP | 
    300:
    PTDYDRSPFV | TSPISMTMPP | HSSLHGYQPY | GHFPSRAIKS | EYPDPYSSSP | 
    350:
    ESMMGYSYMD | GYQTNSPASI | PHLILELLKC | EPDEPQVQAK | IMAYLQQEQS | 
    400:
    NRNRQEKLSA | FGLLCKMADQ | TLFSIVEWAR | SSIFFRELKV | DDQMKLLQNC | 
    450:
    WSELLILDHI | YRQVAHGKEG | TIFLVTGEHV | DYSTIISHTE | VAFNNLLSLA | 
    500:
    QELVVRLRSL | QFDQREFVCL | KFLVLFSSDV | KNLENLQLVE | GVQEQVNAAL | 
    550:
    LDYTVCNYPQ | QTEKFGQLLL | RLPEIRAISK | QAEDYLYYKH | VNGDVPYNNL | 
    560:
    LIEMLHAKRA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    E0297h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    E0297m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    E0297r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    E0297c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    U0297h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    U0297m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    U0297r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    U0297c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Polyclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    P0297Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    P0297Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Cat.:
    P0297Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Monoclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Monoclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Monoclonal Antibody for Mouse Nuclear receptor subfamily 5 group A member 2
    Protein for Mouse Nuclear receptor subfamily 5 group A member 2
    Protein for Mouse Nuclear receptor subfamily 5 group A member 2
    Protein for Mouse Nuclear receptor subfamily 5 group A member 2
    Protein for Mouse Nuclear receptor subfamily 5 group A member 2

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    Linearity
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    References
    1. 1.
      "LRH-1: a nuclear hormone receptor active in the absence of exogenous ligands."
      Tugwood J.D. , Issemann I. , Green S.
      Submitted (1992-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 3.
      "Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1."
      Sablin E.P. , Krylova I.N. , Fletterick R.J. , Ingraham H.A.
      Mol. Cell11:1575-1585(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 313-560;INTERACTION WITH NR0B2 AND GRIP1
    4. 4.
      "Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner."
      Li Y. , Choi M. , Suino K. , Kovach A. , Daugherty J. , Kliewer S.A. , Xu H.E.
      Proc. Natl. Acad. Sci. U.S.A.102:9505-9510(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 318-560 IN COMPLEX WITH NR0B2
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